Cardiac Regenerative Therapy - Is It Viable?

Explore the viability of cardiac regenerative therapy in this 47-minute grand rounds presentation from the University of Washington's Cardiology department. Gain insights into the rationale behind regenerative therapies in cardiovascular medicine, examine the current status of novel cardiac gene- and cell-based therapies, and understand the challenges facing cardiac remuscularization therapy. Delve into topics such as delivery methods, gene therapy targets, clinical trials, autologous skeletal myoblast transplants, and stem cell transplants. Analyze the potential complications, including arrhythmias and immunosuppression, and learn about large animal models and immunotolerance. Conclude with a summary of efficacy and engage in a question-and-answer session to deepen your understanding of this cutting-edge field in cardiology.

Introduction
Cardiac Regeneration
Delivery Methods
Gene Therapy
Targets
Circa 2A
Clinical trials
Revast trial
Cell therapy
Autologous skeletal myoblast transplants
Cardiac remuscularization
Long QT
Rhythmic complications
Engraftment arrhythmia
Preventing arrhythmia
Large animal model
Immunotolerance
immunosuppression
stem cell transplants
summary
questions
efficacy