Universal Influenza Vaccine Update

Explore the latest developments in universal influenza vaccine research presented at ICAAC 2012 in this 32-minute conference talk. Delve into the limitations of current strain-specific vaccines and the pressing need for a universal solution that can protect against any potential influenza strain. Learn about ongoing efforts and recent breakthroughs from experts Donna Ambrosino and Zachary Shriver of Visterra. Gain insights into monocle antibodies, animal models, neutralization data, and vaccine responses. Understand the licensing strategy, epitope conservation, and potential indications for a universal vaccine. Discover who might benefit from such a vaccine and the implications of antihuman antibodies in this comprehensive update on the quest for the "holy grail" of public health.

Introduction
Presentation
Monocle Antibody
How would we use it
Animal models
Neutralization data
Monoclonal antibodies
Vaccine response
Licensing strategy
Is the epitope normally exposed
Is the epitope conserved
The lead candidate
Indications
Who should get the vaccine
Antihuman antibody
Final comments
Outro