The Use of Remdesivir Against SARS-CoV-2 - New Perspectives on Antimicrobial Agents

Explore the use of remdesivir against SARS-CoV-2 in this 48-minute conversation between editors from the American Society for Microbiology. Delve into the rationale behind using remdesivir for COVID-19 treatment, examine clinical data supporting its use, and discuss future studies and knowledge gaps. Learn from experts Dr. Muneerah Aleissa and Dr. Francisco Marty as they review the drug's development, mechanism of action, and clinical trials including the Wuhan study, ACT Trial, and Solidarity Trial. Gain insights into symptom improvement scales, mortality data, and current recommendations for remdesivir use in treating COVID-19 patients.

Introduction
Development of remdesivir
Mechanism of action
Clinical data
Wuhan study
Symptom improvement scales
Act Trial
Act Trial Mortality
Simple Severe and Simple Moderate
Simple Moderate
Solidarity Trial
Comments
Recommendations
Conclusion