The Dynamics of the Unconscious Brain Under General Anesthesia

Explore the intricate dynamics of the unconscious brain under general anesthesia in this 46-minute lecture by Emery Brown, Professor of Brain and Cognitive Sciences at MIT and Professor of Anesthesia at Harvard. Delve into how anesthetic drugs like Propofol alter neural oscillations in the brain, as measured by EEG. Examine a model of the neural circuitry underlying anesthesia's impact on neural signals and discover how these changes vary with age. Learn about potential clinical methods for actively restoring brain function post-anesthesia, which may lead to faster recovery and reduced cognitive dysfunction. Gain insights into the history of anesthesia, balanced general anesthesia, clinical electroencephalography of Propofol, and the differences between general anesthesia and sleep. Investigate the brain's response to anesthesia across different age groups and explore the concept of reanimation from general anesthesia. Understand the science behind anesthesia and its effects on the brain, including the mechanism of Ritalin in relation to anesthesia recovery.

Intro
Main Points The brain under general anesthesia is dynamic and not
What is General Anesthesia?
Brief History of Anesthesia
Balanced General Anesthesia
Clinical Electroencephalography of Propofol
Loss of Consciousness from Propofol
Alpha Oscillations Are Coherent Thalamocortical Rhythms
Slow Oscillations Gate Phase-Limited Spiking Activity
General Anesthesia Is Not Sleep
Defining the Anesthetic State As a Function of Age
The Brain Response to Anesthesia Changes with Age
Awakenings: Reanimation from General Anesthesia
Science from the Word on the Streets
Ritalin Mechanism