The Control of Breathing in Fish - Why and How
Offered By: Society for Experimental Biology via YouTube
Course Description
Overview
Syllabus
The Control of Breathing in Fish - Why and How
George Parker Bidder III (1863-1953)
George Bidder III saves the day!
The world record!
A remarkable man!
Sensing the environment
What is the benefit of hyperventilation?
Empirical evidence for beneficial effects of hyperventilation
Benefits of hyperventilation
Functional studies of gill neuroepithelial cells
Neuroepithelial cells are CO2 sensors
Neuroepithelial cells are ammonia sensors
Rhesus (Rh) glycoproteins and ammonia sensing
HEA causes hyperventilation in larval zebrafish
Are Rh proteins involved?
Rh protein localisation in
in zebrafish larvae
A proposed model for ammonia sensing in zebrafish
Does HIF1a regulate the hypoxic hyperventilatory response?
HVR in wildtype larval zebrafish
HVR in larval zebrafish
Is the stimulatory effect of HIFla on the hypoxic ventilatory response related to nitric oxide?
HIF1a and nitric oxide
The role of 5-HT in chemoreception
Serotonin synthesis
TPH1a knockdown reduces number of detectable NECS
Depletion of NEC serotonin blunts the hypoxic ventilatory response
A model for the involvement of serotonin in chemoreception
Final words
Taught by
Society for Experimental Biology
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