Sedatives and Procedures

Explore the concept of the therapeutic window and its application in sedative drug choices for pediatric procedures in this comprehensive 51-minute video lecture by Dr. Gregory Hollman. Delve into pharmacokinetic and pharmacodynamic principles, examining how they influence sedative selection to achieve optimal therapeutic effects. Learn about various sedative drugs, including chloral hydrate, pentobarbital, etomidate, propofol, dexmedetomidine, midazolam, nitrous oxide, fentanyl, and ketamine, along with their clinical uses and profiles. Gain insights into procedure characteristics and their impact on sedative selection. Conclude with a summary of key points on sedative drugs and their applications in pediatric care.

Intro
THE THERAPEUTIC WINDOW
PHARMACODYNAMICS
PHARMACOKINETICS What the body does to the drug
PHARMACOKINETICS Intravenous Administration
PROCEDURE CHARACTERISTICS
CHLORAL HYDRATE
PENTOBARBITAL
ETOMIDATE Clinical Use
PROPOFOL
DEXMEDETOMIDINE
MIDAZOLAM Clinical Use - Intravenous
NITROUS OXIDE
FENTANYL Profile
KETAMINE
SEDATIVE DRUGS
CONCLUSIONS