Tales from the Genome
Offered By: 23andme via Udacity
Course Description
Overview
This course is a journey into the biology of the human genome and will highlight the scientific, social, and personal perspectives of people living with a variety of traits.
Syllabus
- Origin of mutation/variation
- Types of mutations and various causes of mutation.,Allelic frequency, and the spread of alleles in a population.
- How to obtain and interpret personal genetic information
- Personalized genetics: sample acquisition, DNA extraction and processing.,Interpretation of results.
- Simple genetic traits
- Molecular causes of monogenic traits.,Loss-of-function vs. gain-of-function alleles, and dominance.
- Multifactorial traits
- Polygenic traits, qualitative and quantitative measures.,Twin studies, relative risk, and genome-wide association studies (GWAS).
- Pharmacogenetics: genes and drugs
- Pharmacokinetics and pharmacodynamics.,Alleles affecting drug metabolism.,Personalized medicine.
- Origin of mutation/variation
- Types of mutations and various causes of mutation.,Allelic frequency, and the spread of alleles in a population.
- How to obtain and interpret personal genetic information
- Personalized genetics: sample acquisition, DNA extraction and processing.,Interpretation of results.
- Simple genetic traits
- Molecular causes of monogenic traits.,Loss-of-function vs. gain-of-function alleles, and dominance.
- Multifactorial traits
- Polygenic traits, qualitative and quantitative measures.,Twin studies, relative risk, and genome-wide association studies (GWAS).
- Pharmacogenetics: genes and drugs
- Pharmacokinetics and pharmacodynamics.,Alleles affecting drug metabolism.,Personalized medicine.
Taught by
Matthew Cook
Tags
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