Pharmacokinetics and Pharmacodynamics of Therapeutic Proteins - Part 5
Offered By: NIH Clinical Center via YouTube
Course Description
Overview
Explore the final installment of a five-part lecture series on the pharmacokinetics and pharmacodynamics of therapeutic proteins, presented by Dr. Bernd Meibohm as part of the NIH Principles of Clinical Pharmacology Course. Delve into the crucial topic of immunogenicity and its impact on therapeutic protein efficacy. Examine the various factors that modulate immunogenicity and understand the roles of antidrug antibodies, immune complexes, clearing antibodies, and sustaining antibodies. Conclude with a comprehensive summary, test your knowledge with a self-assessment question, and access recommended further reading materials. Gain valuable insights into this essential aspect of clinical pharmacology, enhancing your understanding of rational drug development and therapeutic utilization.
Syllabus
Introduction
Goals
Immunogenicity
Factors modulating Immunogenicity
Antidrug antibodies
Immune complexes
Clearing antibodies
Sustaining antibodies
Summary
SelfAssessment Question
Further Reading
Taught by
NIH Clinical Center
Related Courses
Farmacología BásicaUniversidad San Pablo CEU via Miríadax Antimicrobial Stewardship: Managing Antibiotic Resistance
University of Dundee via FutureLearn System Dynamics for Health Sciences
University of the Witwatersrand via edX Computer Aided Drug Design
Indian Institute of Technology Madras via Swayam Drug Delivery: Principles and Engineering
Indian Institute of Science Bangalore via Swayam