De Novo Protein Design Using Deep Learning and Musical Representations

Explore cutting-edge research on designing new proteins through an insightful interview with Markus Buehler from the Massachusetts Institute of Technology. Delve into Buehler's innovative approach of using deep learning models trained on musical representations of proteins to create novel protein designs. Learn about the unique architecture of the model, composed of long short-term memory units, and how it processes data classified by specific protein features. Gain understanding of the potential applications and implications of this groundbreaking work in the field of protein engineering, as published in APL Bioengineering. Discover the intersection of materials science, artificial intelligence, and molecular biology in this engaging 24-minute discussion led by Gopal Rao, chief editor for technical content at the Materials Research Society.

Markus Buehler on de novo protein design