Guillain-Barre Syndrome: Pathophysiology, Symptoms, and Treatment - Neurology Lecture

Dive into a comprehensive neurology medicine lecture on Guillain Barre Syndrome (GBS) and its variants, including Miller Fischer syndrome. Explore the pathophysiology, symptoms, diagnosis, and treatment options for this autoimmune disorder affecting the peripheral nervous system. Learn about causative pathogens, clinical presentations, cranial nerve involvement, and diagnostic investigations. Understand the importance of timely management, including indications for intubation and ICU admission. Discover immunomodulatory therapies such as intravenous immunoglobulin (IVIG) and plasmapheresis, along with their administration protocols. Compare GBS with transverse myelitis and gain insights into prognosis and long-term outcomes. This USMLE-focused lecture provides essential knowledge for medical students, residents, and healthcare professionals preparing for exams or seeking to enhance their understanding of this critical neurological condition.

Intro
What is Guillain Barre Syndrome GBS
Causative Pathogens
Pathophysiology
Clinical Presentation
Cranial Nerve Involvement
Subtypes/ GBS Variants Miller Fischer
Diagnosis/Investigations
Treatment
Indications of Intubation
Immunomodulatory Therapy IVIG, Plasmapheresis
How to give IVIG?
Plasmapharesis
Prognosis
Transverse Myelitis vs Guillain Barre syndrome
Summary