Experiments That Point to a New Understanding of Cancer

Explore groundbreaking cancer research in this 16-minute TED-Ed talk by Mina Bissell. Discover how the revolutionary idea that cancer cells rely on their microenvironment for tumor development challenges long-held beliefs. Learn about two pivotal experiments that disproved prevailing wisdom on cancer growth. Delve into topics such as developmental biology, the RSV tumor in chickens, embryonic tumor resistance, mammary gland structure, and the role of extracellular matrix in distinguishing normal and malignant cells. Gain insights into the Bissell Laboratory's innovative approach to understanding cancer progression and potential new avenues for treatment.

Intro
Developmental Biology
RSV Tumor in Chicken Discovered by Rous in 1911
No Tumor in the Embryo
Structure of the Mammary Gland An acinus' is a unit of the functional marmary gland
Structural Organization of Mammary Epithelial cells
ECM (Red) Stanng in Mouse Mammary Gland
A method to distinguish normal and malignant
Testing the Hypothesis
The Bissell Laboratory