Early Exposure to Anesthesia on the Developing Brain

Explore the critical topic of anesthesia neurotoxicity on developing brains in this 56-minute video lecture featuring expert discussions by Drs. Paul Hickey, Charles Berde, Laszlo Vutskits, Mary Ellen McCann, Sulpicio Soriano, Charles A. Nelson, and Lynne Ferrari. Delve into the discovery of sterile apoptosis induced by anesthetic agents, alternative approaches to general anesthesia, and the potential impact of low blood pressure. Learn about local anesthesia, pain medications, and the use of xenon as alternatives. Address crucial questions such as whether parents should postpone surgery, potential downsides, and the comparative safety of different anesthetic methods. Gain valuable insights into the effects of general versus regional anesthesia on developing brains. This comprehensive lecture, presented by OPENPediatrics in collaboration with Boston Children's Hospital and the World Federation of Pediatric Intensive and Critical Care Societies, offers essential knowledge for healthcare providers caring for critically ill children worldwide.

Introduction
Neurotoxicity in the developing brain
How did we discover that anesthetic agents can induce sterile apoptosis
Dr Saul Soriano
Dr Charles Bertie
Low blood pressure
Alternative to general anesthesia
Local anesthesia
Pain medications
Xenon
Lynn Ferrari
Dr Soriano
Should parents postpone surgery
Dr McCann
Downsides
Are there some anesthetics that are safer than others
Is there a significant difference between general anesthesia and regional anesthesia
Closing remarks