Biopsy Interpretation - Dr Hebah Ali

Learn to interpret biopsy samples and generate comprehensive pathology reports in this anatomical pathology lecture. Follow the journey of a biopsy from sample collection to final diagnosis, exploring key diagnostic processes, artifact challenges, and treatment effects on interpretation. Master the art of producing clinically useful histopathology reports while gaining insights into lymphoma patterns, immunohistochemistry basics, and the importance of clinical context in diagnoses. Discover the significance of prior diagnoses and treatments in biopsy interpretation, and understand the elements that constitute a well-written pathology report for effective communication with clinicians.

Intro
Objectives: Follow the Biopsy Journey
The report is out! An Integrated Report
We have received a sample!
The biopsy is being processed! DAY21
The pathologist is 'looking' at the case!
FISH is not ready!
MOLECULAR (CLONALITY) IS OUTSTANDING!
What type of cancer (lymphoma)?
What colour is the neoplasm?
What are the Common Lymphoma Patterns?
Is it enough to play the CDs?
Compare with normal ...
Understand the basis of the IHC
Follicular Lymphoma: Variants
Lymphoma (and other pathologies) are clinical context-sensitive diagnoses
Prior Diagnosis. Why is it important? • History of prior known tumours (including type/site/date of removal/ stage of disease).
Previous Treatment
What is considered a Good Report You are writing to the clinician