Autism Mythbusters - Shafali Jeste, MD - UCLAMDChat

Explore the complexities of autism spectrum disorders in this comprehensive UCLA lecture. Delve into the history of autism, its clinical heterogeneity, and genetic factors influencing early brain development. Learn about cutting-edge research using EEG to study brain-based biomarkers and potential treatment targets. Discover the current mainstay of behavioral interventions, off-label pharmacological treatments for insomnia, and the rise of complementary and alternative therapies. Gain insights into the myths surrounding autism, including the debunked vaccine link, and understand the challenges in developing clinical trials for neurodevelopmental disorders. Join UCLA neurologist Dr. Shafali Jeste as she addresses these topics and discusses ongoing efforts to prevent and potentially cure autism.

Autism Spectrum Disorders: Myth Busters
Financial Disclosures
Talk Outline
History of Autism
Why the Increase?
CHANGES from DSM-IV
Clinical Heterogeneity of ASD
ASD is a Heritable Disorder
UCLA Developmental Neurogenetics Clinic
Genes impact EARLY brain development
Developmental Disconnection
Key Principles in our study of brain based biomarkers in ASD
Electroencephalography (EEG)
Differences in EEG Connectivity
Targets for treatment for ASD
Behavioral intervention is the mainstay of treatment
Insomnia: Pharmacological treatment OFF LABEL
Complementary and Alternative (CAM) Treatments
Diet/Supplements
Clinical trials for neurodevelopmental disorders: At a therapeutic frontier