Evaluating the 23 Gy Kidney Absorbed-Dose Limit for Radiopharmaceutical Therapies

Explore the controversial 23 Gray absorbed dose limit for kidneys in radiopharmaceutical therapies (RPTs) through this informative 18-minute video. Delve into the origins of this seemingly arbitrary limit, tracing its roots to external radiation beam therapy publications from 1991 and 1968. Join Nuclear Jimmy and expert guests Dr. Persi, Dr. Fence, and Mr. RPT as they critically examine the validity of absorbed dose limits for RPTs. Discover key discussion points including outdated literature, homogeneous vs. heterogeneous radiation distribution, observed differences in kidney toxicities between RPTs, dose rate differences, and the importance of microscopic dose deposition. Gain valuable insights into the complexities of RPT dosimetry and the need for updated, therapy-specific guidelines in this engaging and thought-provoking presentation.

Apples or Kiwis? Is 23Gy kidney absorbed-dose limit the way to go for radiopharmaceutical therapies?