3D Bioprinting of Organs Part 1 - MRS OnDemand Webinar

Explore the cutting-edge field of 3D bioprinting in this comprehensive webinar from the Materials Research Society. Delve into the latest advances and challenges in support materials, multimaterials printing, and applications in tissue engineering and organs-on-a-chip. Learn about the displacement of traditional manufacturing methods by additive manufacturing technologies across various industries. Discover the intricacies of solid organ structures, focusing on the multiscale vasculature of the human liver and its structure-function relationships. Examine common additive manufacturing techniques, with a particular emphasis on extrusion bioprinting and its challenges. Investigate strategies and technical solutions for both external and internal stabilization of 3D printed constructs, including examples from current research. Gain insights into methods for adjusting viscosity and the release of materials from crosslinked scaffolds, applicable to various cell types including human mesenchymal stem cells. Conclude with an introduction to core/shell bioprinting techniques, setting the stage for further exploration in this rapidly evolving field.

Intro
3D Bioprinting of Organs
The Bionic Human + Regenerative Medicine Science
Solid Organs have Multiscale Vasculature Human Liver
Structure-Function Relationships
Extrusion Printing
TECHNISCHE UNIVERSITAT DRESDEN
Common AM technologies
Challenges for extrusion bioprinting
3D printed constructs for clinically relevant applications
Main strategies
Technical solutions
External stabilization
Examples (own work)
Internal stabilization
Examples (own work/1)
Adjusting the viscosity
Release of methylcellulose from the crosslinked scaffolds
Suitable for several cell types Human MSC
Core/shell bioprinting