General Biochemistry

This course focuses on contributions of biochemistry toward an understanding of the structure and functioning of organisms, tissues, and cells. Topics include: * Chemistry and functions of constituents of cells and tissues and the chemical and physical-chemical basis for the structures of nucleic acids, proteins, and carbohydrates. * Basic enzymology and biochemical reaction mechanisms involved in macromolecular synthesis and degradation, signaling, transport, and movement. * General metabolism of carbohydrates, fats, and nitrogen-containing materials such as amino acids, proteins, and related compounds. NOTE: The first half of this course, taught by Prof. Yaffe, is available on the MITx platform as _[7.05x Biochemistry: Biomolecules, Methods, and Mechanisms](https://www.edx.org/course/biochemistry-biomolecules-methods-and-mechanisms?utm_source=mitopenlearning-mit-open-learning&utm_medium=affiliate_partner)_. This OCW website provides content primarily from the second half with Prof. Vander Heiden, which focuses on metabolism.

• Lecture 12: Carbohydrates/Introduction to Membranes
• Lecture 19: Introduction to Metabolism/Polysaccharides/Bioenergetics/Intro Pathways
• Lecture 20: Bioenergetics/Intro Pathways/Glycolysis I
• Lecture 21: Glycolysis II/Regulation
• Lecture 22: Glucogenesis/Carbohydrate Storage/TCA Cycle I
• Lecture 23: TCA Cycle II
• Lecture 24: Lipids and Fatty Acid Oxidation
• Lecture 25: Oxidative Phosphorylation
• Lecture 26: Oxidative Phosphorylation/Photosynthesis I
• Lecture 27: Photosynthesis II/CO2 Assimilation
• Lecture 28: Pentose Phosphate Pathway
• Lecture 29: Lipid Synthesis
• Lecture 30: Nitrogen/Amino Acid Metabolism I
• Lecture 31: Amino Acid Metabolism II
• Lecture 32: Nucleotide Metabolism