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The Mathematical Essence of Aging - Theoretically Speaking

Offered By: Simons Institute via YouTube

Tags

Mathematical Modeling Courses Physiology Courses Aging Courses

Course Description

Overview

Explore the mathematical principles underlying aging in this comprehensive lecture by Uri Alon from the Weizmann Institute of Science. Delve into large-scale medical data analysis and the development of simplified mathematical models for complex physiological systems. Discover insights on human hormone seasonality and a stochastic equation for damage accumulation that explains age-related disease incidence. Learn about potential optimal treatments for aging that could reduce multiple age-related diseases by addressing their core processes. The talk covers topics such as demographics, Markov's Law, biology of aging, senescent cells, mouse models, and mathematical assumptions in aging research.

Syllabus

Introduction
Welcome
Who is Shai
What is aging
Demographics
Markovs Law
Biology of Aging
Senescent Cells
Aging
Senescence
Mouse Models
The Role of Mathematics
Sharpless Bird Experiment
Longitudinal Mouse Experiment
Mathematical Model
Questions
Mathematical Assumptions
Extrinsic Mortality
Diseases
Incidence


Taught by

Simons Institute

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