The Literature - How You Can Be Fooled – Jerome Hoffman, MD

Explore the complexities of medical literature interpretation in this thought-provoking lecture from the 33rd Annual EM & Acute Care Course. Delve into topics such as selection bias, reproducibility, risk factors, and patient-oriented evidence. Learn to critically analyze research methods, understand the differences between disease-oriented and patient-oriented outcomes, and evaluate the true effectiveness of treatments like statins and high-dose augmentin. Gain insights on primary prevention, sepsis management, and the importance of considering both harm and benefit in medical decision-making. Develop skills to navigate the challenges of medical literature and improve your ability to provide evidence-based emergency care.

Intro
The Literature
Selection Bias
Who was Robert Cole
Causes of disease
Reproducibility and external validity
Risk factors
People are going to die
I want to follow acutely
Read the methods
Sepsis
Patientoriented evidence
If you have it
Primary prevention
One less heart attack
statin related problems
patient oriented outcomes
disease oriented outcomes
most of the things in medicine are not true
sometimes its not bacterial
highdose augmentin
harm and benefit
primary outcomes
four primary outcomes
we found these outcomes