The Influence of Myocardial Edema on Microvascular Obstruction During ST-Elevation Myocardial Infarction - Cardiovascular Grand Rounds

Explore the influence of myocardial edema on microvascular obstruction during ST-elevation myocardial infarction in this comprehensive 59-minute Cardiovascular Grand Rounds presentation. Delve into the contribution of lethal reperfusion injury to final infarct size, and gain insights into microvascular obstruction (MVO) and its historical perspectives. Examine the development of myocardial edema following reperfusion, its dependence on reperfusion, and how increased extravascular compressive forces contribute to MVO. Investigate the relationship between MVO mass, left ventricular mass, and myocardial edema. Challenge prevailing dogma about infarct size with "out of this world" revelations, and explore left ventricular ejection fraction follow-up and intramyocardial hemorrhage (IMH). Enhance your understanding of these critical aspects of cardiovascular medicine through this in-depth presentation.

The influence of myocardial edema on microvascular obstruction during ST-elevation myocardial infarction
DISCLOSURES
Contribution of Lethal Reperfusion Injury Contributes up to 40% of Final Infarct Size
Microvascular Obstruction (MVO)
MVO is represented by hypo-enhanced (orange) region inside the hyper-enhanced (yellow) infarct region
MVO (no-Reflow) - Historical Perspectives
Myocardial Edema Following Reperfusion - Background
Development of Myocardial Edema is Dependent on Reperfusion
Increased Extravascular Compressive Forces Contribute to MVO
MVO Mass Increases Linearly with LV Mass and is associated with Greater Myocardial Edema
"Out of this World" Revelations About Infarct Size Following STEMI !
Prevailing Dogma about Infarct Size
LVEF Follow-up
Intramyocardial Hemorrhage (IMH)