The Immunology of COVID-19: Pathology and Clinical Implications

Explore the immunology of COVID-19 and its clinical implications in this expert-led seminar presented by Dr. Alex Richter, Senior lecturer and Consultant in Clinical Immunology at the Institute of Immunology and Immunotherapy. Delve into topics such as the initial viral infection, innate immune response, T-cell and antibody responses, and the use of antibody testing in public health. Gain insights into clinical interpretations, measuring T-cell and B-cell responses, paraprotein production, neonatal antibodies, reinfection possibilities, and post-COVID syndrome. Learn about in-house assays, antibody tests, and the timescale for T-cell response. This 41-minute seminar, part of The Royal College of Pathologists' COVID-19 pandemic series, is introduced by virologist and College Fellow, Professor Will Irving, and offers a comprehensive look at the pathology and impact of COVID-19 on the field of immunology.

Introduction
What is the threat
Initial viral infection
Innate immune response
Tcell response
Antibody response
Why use antibodies
Antibody testing in public health
Clinical interpretation
Questions
Tcell responses
Measuring Tcell responses
Measuring Bcell responses
Paraprotein production
Neonatal antibodies
No trace of antibodies
Can you get reinfected
Antibodies
Joint inflammation
Postcovid syndrome
Inhouse assays
Antibody tests
Timescale for Tcell response