The Hallmarks of Cancer - A Mathematical Perspective

Explore the mathematical perspective on cancer biology in this 1-hour 18-minute lecture by Thomas Hillen from the University of Alberta. Delve into the Mathematics of the Hallmarks of Cancer, examining both top-down and bottom-up approaches to mathematical modeling of cancer. Learn about proliferative signaling, growth suppression avoidance, cell death resistance, replicative immortality, angiogenesis, metastasis, and local invasion. Investigate the application of differential equations in understanding tumor-promoting inflammation and the Weber Effect. Gain insights into how mathematical frameworks can enhance our comprehension of cancer's complex biological processes and potentially contribute to the development of more effective treatment strategies.

Intro
Mathematical Modeling of Cancer
Top Down and Bottom Up
Data
The HKS
Proliferative Signaling
Avoiding Growth Suppression
Resisting Cell Death
Enabling Replicative immortality
Angiogenesis
Metastasis
Local Invasion
Differential Equations
Tumor Promoting Inflammation
The Wber Effect