Systemic Lupus Erythematosus

Learn about Systemic Lupus Erythematosus (SLE) in this comprehensive physician grand rounds presentation by Dr. Scott A. Vogelgesang, a rheumatology expert from the University of Iowa. Explore the epidemiology, natural history, and pathophysiology of SLE, using the mnemonic SOAP BRAIN MD to understand its various manifestations. Delve into specific symptoms and complications, including oral/nasal ulcers, cutaneous involvement, photosensitivity, serositis, and effects on pulmonary, cardiac, musculoskeletal, and neuropsychiatric systems. Examine renal and hematologic implications, as well as immunologic aspects. Discover treatment options, including NSAIDs, hydroxychloroquine, corticosteroids, cyclophosphamide, mycophenolate, belimumab, and rituximab, with a focus on therapy for glomerulonephritis. Gain valuable insights into managing SLE and learn about factors to avoid for better patient outcomes.

Intro
Outline
Epidemiology
Natural History
Pathophysiology
Mnemonic: SOAP BRAIN MD
Oral/Nasal Ulcers
Cutaneous (continued)
Photosensitivity
Serositis
Pulmonary
Cardiac
Musculoskeletal
Neuropsychiatric
CNS Lupus
Renal
Questions?
Hematologic
Immunologic (continued)
New!
NSAIDS
Hydroxychloroquine
Corticosteroids
Cyclophosphamide
Mycophenolate
Belimumab
Rituximab
Therapy: Glomerulonephritis
Avoid
Summary