Theragnostic 3D Ultrasound Imaging System for High-Resolution Image-Guided Therapy - Winter 2022

Explore a theragnostic 3D ultrasound imaging system for high-resolution image-guided therapy in this Stanford Radiology PHIND Winter 2022 lecture. Delve into the principles of ultrasound imaging, ultrafast imaging paradigms, and challenges in clinical ultrasound. Learn about wider arrays, the 1024-channel system, and large aperture geometries including ring and 2D arrays. Discover optimization techniques for image-guided gene delivery, design geometry, and imaging performance. Examine 2D plane wave compounding, image formation processes, and the importance of elevation focusing. Investigate ex vivo assessment of microbubble sonication and strategies to optimize 1024 channels for small lesion detection. Gain insights into breast imaging applications and explore a wide range of potential clinical uses for this advanced imaging technology.

Intro
Principles of ultrasound imaging
Ultrafast imaging: a new paradigm for ultrasound
Challenges of clinical ultrasound imaging
Wider arrays → more elements and more data The 1024-channel system
Large aperture geometries - ring array
Large aperture geometries - 2D array
How to optimize image-guided gene delivery?
How to fix the design geometry?
The imaging performance on point targets at 10 cm
Final design and steering capabilites
2D plane wave compounding
The image formation process
The importance of elevation focusing
Ex vivo assessment of microbubble sonication
How can we optimize 1024 channels to detect small lesions ?
Application to breast imaging (R01 CA258807) Awarded Dec 15th 2021
A wide range of clinical applications