Relating the Structure of the Brain to Its Function by Tracking a Net-Wave of Spikes
Offered By: MITCBMM via YouTube
Course Description
Overview
Explore the intricate relationship between brain structure and function through a comprehensive examination of spike propagation in the visual hierarchy. Delve into the Allen Brain Observatory's high-resolution 3D atlas and high-throughput pipeline for neural imaging. Discover advanced techniques such as surgically intrinsic imaging, neural pixel technology, and neuropixel workstations. Investigate the mapping of function onto structure, hierarchy scoring, and anatomical connectivity. Compare optical and electrical recording methods in the visual cortex during active behaviors. Learn about decoding techniques, the Openscope project, and small-world connectivity. Discuss accumulation of adaptation, invasive experiments, developmental studies, and the relationship between consciousness and intelligence. Explore Cloudstream technology and compare mouse and human brains. Gain valuable insights into cutting-edge neuroscience research and methodologies.
Syllabus
Introduction
Welcome
Allen Brain Observatory
High resolution 3D atlas
High throughput pipeline
Standard surgically intrinsic imaging
High resolution cost platform registration
New data without borders
Cellular data
Neural pixels
Neuropixel workstations
Mapping function on structure
Hierarchy score
Anatomical connectivity
Optical recording vs electrical recording
Electrical recording
Visual cortex
Active behaviors
Decoding
Openscope
Summary
Questions
Smallworld connectivity
Accumulation of adaptation
Invasive experiments
Developmental studies
Consciousness and intelligence
Cloudstream
Are mice and humans the same
Conclusion
Taught by
MITCBMM
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