Pharmacology - Cancer Drugs – Cell Cycle Inhibitors

Explore the mechanisms of action and side effects of various cancer drugs in this comprehensive pharmacology video. Delve into cell cycle-specific agents like topoisomerase inhibitors and microtubule inhibitors, as well as cell cycle non-specific agents including antitumor antibiotics, alkylating agents, platinum coordination complexes, tyrosine kinase inhibitors, and monoclonal antibodies. Learn about specific drugs such as Irinotecan, Paclitaxel, Doxorubicin, Cyclophosphamide, Cisplatin, Imatinib, and Trastuzumab. Gain insights into how these medications target fast-dividing cells at different phases of the cell cycle to combat cancer growth. Cover important topics like DNA damage induction, one-electron redox cycle of anthracyclines, and the targeting of specific receptors like BCR-ABL, HER2, PDGF, VEGF, and EGF.

Overview
Topoisomerase Inhibitors
Microtubule Inhibitors
Antitumor Antibiotics
Alkylating Agents
Platinum Coordination Complexes
Tyrosine Kinase Inhibitors
Monoclonal Antibodies
Side Effects