Nucleophilic Acyl Substitution Reaction Mechanism - Carboxylic Acid Derivatives, Organic Chemistry

Explore the intricacies of nucleophilic acyl substitution reactions in this comprehensive 38-minute organic chemistry video tutorial. Delve into the reaction mechanisms of carboxylic acid derivatives, covering a wide range of topics from acid chloride reactions to cyclic anhydride formation. Learn how to predict major products, understand tetrahedral intermediates, and master various hydrolysis mechanisms. Tackle practice problems and examples on acid-catalyzed and base-promoted reactions, ester and amide formations, lactone synthesis, and nitrile conversions. Gain valuable insights into the behavior of cyclic compounds such as lactams and anhydrides. Perfect for students seeking to enhance their understanding of organic chemistry principles and reaction mechanisms.

Introduction
Acid Chloride and Alcohol
Acid Chloride and Ammonia
Acid Chloride and Amine
Acidic Conditions