New Options for Treating GERD – Beyond PPIs - David C. Chen, MD - UCLA Digestive Disease

Explore new treatment options for gastroesophageal reflux disease (GERD) beyond proton pump inhibitors (PPIs) in this informative lecture by Dr. David C. Chen from UCLA Digestive Disease. Delve into the limitations of PPIs, indications for surgery, and goals of interventional therapy. Discover various alternatives for GERD treatment, including endoscopic therapies like Transoral Incisionless Fundoplication (EsophyX) and Radiofrequency Ablation (Stretta). Learn about surgical options such as Nissen and Toupet Fundoplication, and gain insights into the LINX Magnetic Sphincter Augmentation device. Understand the mechanism of action, efficacy, and potential side effects of these treatments, as well as their impact on patient satisfaction and PPI usage discontinuation.

Intro
Gastroesophageal Reflux: Treatment
Gastroesophageal Reflux: Limitations of PPIS
Indications for Surgery: Gastointestinal Indications
Goals of Interventional Therapy
Gastroesophageal Reflux: Alternatives
The Treatment Gap
Gastroesophageal Reflux: Endoscopic Therapies
Endoscopic Therapies: Commercially Available
Transoral Incisionless Fundoplication: Esophyx
Radiofrequency Ablation: Stretta
Endoscopic Therapies: Currently Being Studied
Endoscopic Stapling System: MediGus SRS
Endoscopic Therapies: No Longer Available
Gastroesophageal Reflux: Surgical Options
Surgical Options: Nissen Fundoplication
Surgical Options: Toupet Fundoplication
Fundoplication Versus Medical Management
Surgical Options: LINX Magnetic Sphincter Augmentation FDA PMA approved March 2012
Mechanism of Action
LINX: Overview
LINX: Reduction in Esophageal Acid Exposure
LINX: Discontinuation of PPI Use
LINX: Patient Satisfaction
LINX: Side Effects
LINX: Treatment Efficacy