Introduction to Microfluidics

Explore the fundamentals of microfluidics in this comprehensive lecture by Prof. Terence Kuzma from Pennsylvania State University. Delve into the unique physics of fluids at the microscale, learn about modern manufacturing processes for creating lab-on-a-chip devices, and discover solutions to overcome associated challenges. Gain insights into the fabrication of microfluidic channels through a hands-on experience in a teaching cleanroom, complete with detailed recipes. Examine the simulation of a microfluidic channel designed to separate red blood cells as a practical application. Cover topics such as micro arrays, advantages and disadvantages of microfluidics, electro-osmosis, laminar flow, Reynolds number, Peclet number, mixers, common materials used in microfluidics, and the dimensions of gene chips.

Introduction to Microfluidics
Outline
What is Microfluidics
What is Microfluidics
Micro Arrays
Micro Arrays
Advantages/Disadvantes
Growth of Microarrays
Growth of Microarrays
Outline
Physics of Microfluidics
Electro-osmosis
Electro-Osmonic Flow EOF
Some Non-ideal Considerations
Laminar Flowis the Norm
Laminar Flow
Reynolds Number estimating mixing
Reynolds Number
Reynolds Number Effects
Reynolds Number
Laminar flow depends upon boundary geometry
Water in a 50 um channel
Peciet Number diffusion
Mixers simple design to mix
Mixers
Common Materials
Common Materials
Common Materials
Common Materials
Common Materials
Common Materials cheap stuff
Dimensions of a gene chip
Conclusion