Molecules, Movement, and Motors - Shedding Light on Motor Function

Explore the fascinating world of molecular motors in this lecture featuring Steven M. Block from Stanford University. Delve into single-molecule biophysics, focusing on kinesin and its movement mechanisms. Learn about optical traps, force clamps, and the handover-hand motion of kinesin. Discover how experiments, statistics, and the Michaelis-Menten curve contribute to understanding molecular mechanics. Gain insights into the chemistry and mechanics behind kinesin's function, and explore the concept of "Robokinesin." Conclude with closing remarks by Samara Reck-Peterson from Harvard Medical School, tying together the intricate details of molecular movement and motor function.

Intro
Single Molecule Biophysics
Phylogenetic Trees
Kinesin
Optical Trap
Force Clamp
Kinesin Movement
Handoverhand motion
Force velocity curve
How do we know its asymmetric
How do we walk
Robokinesin
Chemistry and Mechanics
Experiments
Statistics
Randomness
Michaelis Menten curve
Cycle for both heads
Fit
Acknowledgement
Kinesins