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Modeling of Nucleosome Clustering in Euchromatin Resulting from Reader Protein Interactions

Offered By: Center for Physical Genomics and Engineering via YouTube

Tags

Computational Biology Courses Epigenetics Courses Molecular Dynamics Courses Polymer Physics Courses Biophysics Courses Nucleosomes Courses

Course Description

Overview

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Explore a 25-minute talk by Joseph Wakim, PhD Candidate from the Spakowitz Group at Stanford University, on modeling nucleosome clustering in euchromatin. Delve into the fundamental chemical and physical phenomena underlying chromosomal organization and dynamics. Learn about the diverse theoretical and computational methods employed, including analytical theory of semiflexible polymers, polymer field theory, and Brownian dynamics simulation. Gain insights into the multidisciplinary approach used to capture phenomena across various length and time scales. Understand how this research contributes to the broader themes of the Spakowitz lab, which include protein self-assembly, polymer membranes, and charge transport in conducting polymers. Discover the implications of this work for physical genomics and cancer research, supported by the Center for Physical Genomics and Engineering at Northwestern University and the Cancer and Physical Sciences Program at the Robert H. Lurie Comprehensive Cancer Center.

Syllabus

Modeling of Nucleosome Clustering in Euchromatin Resulting from Interactions Between Reader Proteins


Taught by

Center for Physical Genomics and Engineering

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