Making a Diagnosis of Non-Alcoholic Steatohepatitis - UCLA Digestive Diseases

Learn about the diagnostic process for non-alcoholic steatohepatitis (NASH) in this informative lecture from the 10th Annual UCLA-Mellinkoff Gastroenterology and Hepatology Symposium. Explore the NAFLD spectrum, secondary causes, and diagnostic criteria for NASH. Discover the limitations of current diagnostic tools and the importance of ALT levels in predicting liver-related outcomes. Examine various non-invasive tests, including FIB-4 and elastography, and their effectiveness in assessing NASH. Gain insights into combination assessment methods and the promising MRI-based MAST score for identifying patients with NASH and significant fibrosis. Enhance your understanding of this complex liver condition and its diagnostic challenges through a comprehensive case presentation and expert analysis.

Intro
CASE PRESENTATION
What's in a name
NAFLD Spectrum
NAFLD Diagnosis
Secondary causes of NAFLD
NASH Diagnosis
NASH can exit with normal ALT
ALT associated with liver-related outcomes
Other biochemical abnormalities with NASH
Non Invasive Tests (NITS)
FIB-4 predicts liver outcomes in NAFLD
Limitations of elastography
Combination Assessment
MRI-based (MAST) score identifies patients with NASH and significant fibrosis
Summary