Log2 Fold-Change & DESeq2 Model in a Nutshell

Explore the fundamentals of log2 fold-change and the DESeq2 model in this 21-minute video from LiquidBrain Bioinformatics. Gain insights into the importance of using log2FC and understand the workings of DESeq2. Learn about fold change, the rationale behind log2 fold change, challenges in differential expression analysis, and the theoretical foundation of DESeq2. Dive into a practical explanation of DESeq2 R script implementation. Access additional resources, including a reputable training hub for Differential Expression Analysis, the DESeq2 publication, and Bioconductor vignettes. Connect with the instructor through various platforms for further information and support in bioinformatics.

What is fold change?
Why use log2 fold change?
Differential expression analysis - the challenges
Theory behind DESeq2
DESeq2 R script explains