Liver Disorders - Hepatitis B - Steven-Huy Han, MD, UCLA - UCLA Digestive Diseases

Explore a comprehensive lecture on Hepatitis B delivered by Dr. Steven-Huy Han at the UCLA-Mellinkoff Gastroenterology and Hepatology Symposium. Delve into the global impact of Hepatitis B, its transmission methods, and long-term carrier statistics. Understand the progression of the infection, diagnostic techniques using serum markers, and the REVEAL study findings. Learn about antiviral therapy indications for various stages of chronic Hepatitis B, including HBeAg positive and negative cases, as well as compensated cirrhosis. Examine the American Gastroenterological Association's guidelines on preventing and treating Hepatitis B reactivation during immunosuppressive drug therapy. Explore strategies for eradicating chronic HBV, types of control and cure, and potential curative regimens. Gain valuable insights into this devastating global healthcare issue and the latest advancements in its management and treatment.

Intro
Hepatitis B is a Devastating Global Healthcare Issue
Where Are the Long-term HBV Carriers?
How Do You Acquire the Infection in the West?
Outcome of HBV by Age of Infection
Elimination of HBV Transmission
Progression of Hepatitis B Infection
Diagnosis of HBV Infection: Using Serum Markers
REVEAL Study
Indications for antiviral therapy HBeAg Positive CHB
Indications for antiviral therapy HBeAg Negative CHB
Endpoints of antiviral therapy HBeAg Negative CHB
Indications for antiviral therapy Compensated Cirrhosis
American Gastroenterological Association Institute Technical Review on Prevention and Treatment of Hepatitis B Virus Reactivation During Immunosuppressive Drug Therapy
AGA Institute Guidelines on Hepatitis B Reactivation Clinical Decision Tool
Strategies to Eradicate Chronic HBV
Type of Chronic HBV Control and Cure
What Might a HBV Curative Regimen Look Like?
Conclusions