YoVDO

Prediction of Multi-Class Peptides by T-Cell Receptor Sequences with Deep Learning

Offered By: BIMSA via YouTube

Tags

Deep Learning Courses Bioinformatics Courses Neural Networks Courses Immunology Courses Peptides Courses

Course Description

Overview

Save Big on Coursera Plus. 7,000+ courses at $160 off. Limited Time Only!
Explore a cutting-edge deep learning approach for predicting multi-class peptides using T-cell receptor (TCR) sequences in this conference talk from the International Conference on Bioinformatics and Systems Biology (ICBS) 2024. Delve into the innovative methodology that combines TCR sequence vectorization, similarity networks, and V/J gene information to overcome limitations of existing binary outcome models. Learn how this novel framework enhances prediction performance by integrating encoded TCR sequences, node embeddings, and V/J genes. Discover the process of training a sequence embedding model, constructing TCR networks using NAIR, and employing node embedding techniques to capture structural information. Gain insights into the four-fully-connected-layer prediction model used to determine TCR-peptide binding probabilities. Examine the effectiveness of various graph neural networks in identifying potential antigen targets, and understand the implications of this research for advancing our understanding of the immune system and developing new treatments for diseases like cancer.

Syllabus

Li Zhang: Prediction of Multi-Class Peptides by T-cell Receptor Sequences withDeepLearning #ICBS2024


Taught by

BIMSA

Related Courses

Neural Networks for Machine Learning
University of Toronto via Coursera
Good Brain, Bad Brain: Basics
University of Birmingham via FutureLearn
Statistical Learning with R
Stanford University via edX
Machine Learning 1—Supervised Learning
Brown University via Udacity
Fundamentals of Neuroscience, Part 2: Neurons and Networks
Harvard University via edX