Hypofractionation & Positioning - Relatively New Approaches in Breast Cancer Radiation

Explore new approaches in breast cancer radiation therapy through this 45-minute physician grand rounds presentation. Delve into hypofractionation and positioning techniques as Dr. John Hardie from McFarland Clinic discusses radiobiology, statistics, and cell measurements. Examine the linear quadratic model, radiation effects, and the concept of alpha-beta ratios. Analyze hypofractionation curves, equivalency studies, and results from Canadian trials, including DCIS cases. Evaluate heart dose considerations, risk-benefit analyses, and compare conventional breast plans with deep inspiration and prone positioning methods. Gain insights into cardiac toxicity and draw conclusions on these relatively new approaches to improve breast cancer radiation treatment.

Introduction
Outline
Evaluation
Radiobiology
Statistics
Cell Measurements
Linear Quadratic Model
Radiation
Split it up
Alpha Beta
ISO Example
Theory Theory Theory
Hypofractionation
Curves
equivalency analysis
Canadian trial results
Canadian trial 2
DCIS
Heart Dose
Risk Benefit Analysis
Conventional Breast Plan
Deep Inspiration
Prone Positioning
Metaanalysis
Cardiac toxicity
Conclusions