Gene Specific Cancer Associations and Sensitivity of Genetic Testing Criteria

Explore gene-specific cancer risk associations and the sensitivity of genetic testing criteria in this informative webinar. Delve into findings from a large laboratory-based multigene panel cohort study, comparing testing cases to reference controls from gnomAD. Examine the prevalence of pathogenic variants across different clinical testing indications. Investigate the sensitivity of BRCA1/2 and Lynch syndrome testing criteria, identifying opportunities for improved detection of cancer-predisposing germline variants. Learn from expert presenters Holly LaDuca, MS, CGC, and Sarah Campian, MS, CGC, as they guide you through study demographics, proband and family cancer histories, and the proportion of cases meeting testing criteria. Gain insights into recent updates to NCCN guidelines and access additional resources through the provided open-access link.

Intro
BACKGROUND
STUDY POPULATION
DEMOGRAPHICS
PROBAND CANCER HISTORY
FAMILY CANCER HISTORY
PROPORTION MEETING TESTING CRITERIA
SUMMARY
METHODS
SENSITIVITY OF BRCA1/2 TESTING CRITERIA
SENSITIVITY OF LYNCH TESTING CRITERIA
LIMITATIONS
CONCLUSIONS
RECENT UPDATES TO NCCN GUIDELINES
LINK TO OPEN ACCESS