Functional Genomics

PRE-REQUISITES: Basic level of understanding in cell and molecular biology is expected.

INDUSTRIES APPLICABLE TO: Industries that will recognize this course Biotechnology, medical and pharma companies, paramedic clinical centers, and educational institutes.

INTENDED AUDIENCE: Students interested in pursuing research in genomics and biotechnology field. Medical students and practicing clinicians interested in genomics and molecular medicine. Students interested in careers in biotechnology and biopharma fields. Technical staff /scientists working in biotechnology, biopharma and molecular diagnostic laboratories/industry.

COURSE OUTLINE: With the emergence of high throughput DNA sequencing technologies, the complete genome sequences of many organisms are deciphered and are being analyzed. Despite the progress, understanding the cellular functions of most of the genes thus identified remains a challenge. The emerging field of “Functional Genomics” aims at providing comprehensive approaches to understand the genome functions, to develop and promote high throughput and large scale approaches to investigate the function of the genomes, their products and the interactions between the two. This course thus will provide an overview of the concept of Functional Genomics and contemporary approaches used to understand the genome function.

Introduction to Functional Genomics.
The Genomics Era.
Epigenetics.
Forward Genetics vs Reverse Genetics.
Genome Editing Approaches (Part 1).
Genome Editing Approaches (Part 2).
Transcriptomics (Part 1).
Transcriptomics (Part 2).
Genome Sequence Databases.
DNA Sequencing Methods (Part 1).
DNA Sequencing Methods (Part 2).
Applications of Next-Generation Sequencing (NGS).
Tutorial (Session 1).
Tutorial (Session 2).
Genomic Insight into Evolution.
Genome sequence: Different Questions, Different Comparisons.
Outcome of Comparative Genomics.
Laboratory Session 1.
Laboratory Session 2.