Emerging Therapies for Upper Tract Urothelial Carcinoma - Nicholas Donin, MD - UCLAMDChat

Explore emerging therapies for upper tract urothelial carcinoma in this informative lecture by UCLA urologist Nicholas Donin, MD. Learn about a novel treatment involving a thermosensitive polymer that enables sustained chemotherapy delivery directly to upper urinary tract tumors. Discover the latest data from a randomized clinical trial, understand the challenges of treating this rare disease, and gain insights into various treatment paradigms. Delve into topics such as disease characteristics, current treatment options, the benefits and drawbacks of surgery, and the potential of combining chemotherapy with surgery to improve patient outcomes. The lecture concludes with a Q&A session addressing audience inquiries.

Introduction
Upper Tract Urothelial Carcinoma
Rare disease
Signs and symptoms
Grade
Treatment
Benefits
Disadvantages
Alternative treatments
Disadvantages of surgery
Medical therapy
Upper tract
New therapy
Ice gel
Preclinical work
In humans
Trial
Treatment Paradigms
Chemotherapy and Surgery
Can chemotherapy and surgery improve survival
The Poud Trial
Poud Trial Summary
Why not chemotherapy after surgery
Loss of a kidney
Who should get chemotherapy before surgery
Studies of chemotherapy before surgery
Audience Questions