Electronic Systems for Cancer Diagnosis

This course is designed with an aim of educating students on the process flow for designing electronic systems for tissue-based cancer diagnosis. An exposure towards developing strategies to discriminate pathological cells from normal ones based on the electrophysiological properties of cells. Design and integrate biochip with electronic module for understanding the electro-thermo-mechanical properties of tissues. microtechnology and its use to fabricate sensors and systems. Students will have exposure towards how to fabricate the sensors and their application in real world. Several examples of engineering devices used in clinical research will be also covered. Both conventional (class 1000) and non-conventional (class 10000) cleanroom and some equipment within it will also be shown. Below are some of the course outcomes. The first objective of this course is to understand cancer and its properties: Breast Cancer and Oral Cancer. The second objective is to educate the students on the process flow for designing electronic systems for tissue-based cancer diagnosis. The third objective is to develop skills to design electronic systems for cytology-based studies. Fourth objective is to develop skills to integrate biochips with electronic systems for cancer diagnosis The fifth objective is to understand how to work in a conventional (class 1000) and non-conventional (class 10000) cleanroom environment and understand several equipments. The final objective is to learn and understand in detail how to design electronic systems with the preexisting knowledge of basic electronics and to add on the 3D printing skills.   INTENDED AUDIENCE: Engineering Students, Faculty from Engineering Colleges PREREQUISITES: Basic Electronics/Microfabrication INDUSTRY SUPPORT: NILL

Intro Electronic Systems for Cancer Diagnosis.
Tissue and Cell Culture Techniques: Introduction.
Tissue and Cell Culture Techniques: Methods.
Tissue and Cell Culture Techniques: Devices.
Cleanroom Equipments.
Cleanroom Equipments Contd….
Breast Cancer and Oral Cancer Statistics.
Fabrication of Piezoresistive Sensor.
Fabrication of MEMs-based Biochip for cancer diagnosis.
Fabrication of MEMS-based sensor for electro-mechanical phenotyping of breast cancer.
Silicon substrate devices for breast cancer diagnosis.
Portable Cancer Diagnostic Tool Using a Disposable MEMS-Based Biochip.
Assemby of the electro-mechanical sensor.
Cytology - A detail study on Spin Coater and Cytospin.
Comparitive study on diagnostic tools for oral cancer screening.
Understanding the methods and mechanism to study cell morphology.
Techniques in oral cytology studies.
Fabrication of electro-mechanical sensor contd...
Techniques in cell morphology analysis.
Mechanical Phenotyping of Breast Cancer using MEMS.
Electrical characterization of Breast Tissue Cores.
Basic building blocks of Electronics System: Signal Conditioning Circuits.
Basic building blocks of Electronics System: Data Converteres (contd.. ).
Basic building blocks of Electronics System: Data Converteres.
Basic building blocks of Electronics System: Filters (contd..).
Basic building blocks of Electronics System: Filters.
Basic building blocks of Electronics System: Amplifiers.
Basic building blocks of Electronics System: Filters (contd.).
Etching Process and Figure of Merits.
ECG Signal Processing to calculate BPM (contd).
ECG Signal Processing to calculate BPM (contd.).
ECG Signal Processing to calculate BPM (contd..).
ECG Signal Processing to calculate BPM.
ECG Signal Processing to calculate BPM [contd...].
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NPTEL Lecture 68.