Detection of Carbapenemases - Editors in Conversation

Explore the critical topic of carbapenemase detection in clinical laboratories through this informative 45-minute conversation with Dr. Patricia Simner, an expert in the field. Delve into the significance of identifying these antibiotic-resistant enzymes and their impact on patient care. Learn about various testing methods, including phenotypic and genotypic approaches, and gain practical advice on selecting the most suitable test for your laboratory. Discover the classification of carbapenemases, understand which bacteria should be tested, and examine specific tests such as the Modified Hodge Test, Karba NP Test, MSIM Test, and lateral flow assays. Gain insights into Dr. Simner's research and the current practices in her laboratory, while understanding the urgent threat posed by carbapenem-resistant bacteria as identified by the CDC in 2019.

Introduction
Why is carbapenemases important
Classification of carbapenemases
Which bacteria should be tested
Phenotype and genotypic testing
Modified hodge test
Karba NP test
MSIM test
Lateral flow test
The study
The genotypic test
Which tests are you using
Are there additional tests in your lab