Computation in the Brain - Part 1

Explore the foundations of computational neuroscience in this IEEE tutorial. Delve into the historical origins of neuroscience, tracing its development from ancient Greece to modern times. Learn about key discoveries and pioneers in the field, including the synapse, neurotransmitters, and ion channels. Examine the groundbreaking work on vision by Hubel and Wiesel, and understand the contributions of David Marr to computational neuroscience. Investigate the structure and function of different brain regions, including the cerebral cortex, and discover the fascinating world of place cells and grid cells. Gain insights into how the brain processes information and computes, setting the stage for further exploration of this complex and fascinating field.

Intro
Three parts
Neuroscience: the origins Alcmaeon of Croton 520 BC.
Neuroscience Timeline (cont.) L. Galvani 1760
Neuroscience is Born!
1932: C. Sherrington: the synapse
Plasticity!
1936: H. Dale and O. Loewi: neurotransmitters • The chemical language of neurons
Neurotransmitters: many kinds (from Wikipedia)
1970: Katz, von Euler, Axelrod: synaptic vesicles
1991: Neher - Sakmann; 2000: Carlsson, Greengard, Kandel: ion channels
1963: Eccles, Hodgkin, Huxley: the spike
The spike, how?
1981: Sperry, Hubel, and Wiesel: vision
The Hubel - Wiesel conjecture: simple cells
The Hubel - Wiesel conjecture: complex cells
David Marr (1945 – 1980) and the genesis of computational neuroscience
2006: R. Axel and L. Buck: olfaction
OK, the parts of the brain
Btw, parts of the brain?
Parts of the brain names: Bones of the skull
Parts of the brain names: directions
(Cerebral) Cortex: the engine
Place cells
Grid cells