Antibiotic Resistant Bacteria

Explore the critical issue of antibiotic-resistant bacteria in this compelling lecture from the American Society for Microbiology. Delve into the 2011 outbreak of carbapenem-resistant Klebsiella pneumoniae at the NIH Clinical Center, a pathogen topping the CDC's list of urgent threats. Learn how Dr. Julie Segre, a senior investigator at the National Human Genome Research Institute, utilized cutting-edge DNA sequencing to trace the outbreak's origin and spread. Gain insights into the growing global challenge of antibiotic-resistant infections, particularly in hospital settings. Discover the importance of infection control measures, including hand hygiene and contact isolation. Examine the role of next-generation sequencing in combating these dangerous pathogens and the challenges of implementing patient-specific sequencing. Understand the significance of hospital surveillance programs in detecting and managing antibiotic-resistant bacteria. This Elizabeth O. King Lecture offers a comprehensive look at the intersection of genomics, microbiology, and public health in addressing one of the most pressing medical challenges of our time.

Introduction
Klebsiella pneumoniae
NIH Clinical Center story
Human Genome Project
Hand Hygiene
Contact Isolation Unit
Local ShortTerm Hospitals
CRE Hospital Surveillance Program
Sequencing Center
Conclusions
Conclusion
Questions
Comments
Infection Control
Next Generation Sequencing
Challenges to Patient Specific Sequencing