Tiling the Genome - Naming the Parts of Your Genome That Make You You

Explore the intricacies of genomic science in this 42-minute lecture from the DNA Lecture Series at Harvard University's Radcliffe Institute for Advanced Study. Delve into the concept of "tiling the genome" and its potential impact on precision medicine with Alexander (Sasha) Wait Zaranek, chief scientist at Curoverse Inc. and director of informatics at the Harvard Personal Genome Project. Learn about the challenges and opportunities in organizing computational resources for genomic analysis, the importance of sharing and privacy in genomic data, and the role of open-source platforms like Arvados. Discover how clinical genetics and tools such as Principal Component Analysis are shaping our understanding of individual genomes. Gain insights into the future of personalized healthcare as Zaranek discusses the potential for doctors to utilize individual DNA information in medical practice.

Intro
My genome
Making sense of genomes
We need lots of genomes
How are we going to do this
Free Software Foundation
The Personal Genome Project
How do we organize computational resources
What do we have now
Features of a big data platform
Sharing
Privacy
Provenance
Paris Hilton
Ribosome Base
Arvados
Open Source
Lightning
Clinical Genetics
Alexanders Genome
Genome Diagram
Principal Component Analysis
federated
conclusion