ABO Blood Group System - Hematology

Dive into a comprehensive 48-minute hematology lecture exploring the intricacies of the ABO Blood Group System. Learn about the nature of A, B, AB, and O blood groups, the role of H antigen as a precursor to RBC antigens, and the functions of N-Acetyl Galactosamine (NAGA) Transferase and B transferase in antigen formation. Understand the relationship between genotypes and phenotypes in different blood groups, the genetic basis of the ABO system, and the concepts of dominant and recessive alleles. Gain insights into why the AB blood group is named as such and the reasons behind the O blood group designation. This in-depth exploration covers essential topics in hematology, making it valuable for medical students and professionals seeking to enhance their understanding of blood group systems.

Introduction to ABO and Rh blood group systems
Antigens and their relation with different blood groups
H substance/antigen and its origin
Origin of Blood group A antigen and its relation with H antigen, Role of N-Acetyl Galactosamine NAGA Transferase/Transferase A
Blood group B antigen in relation to H antigen Role of B transferase
Comparison between blood group A antigen and blood group B antigen
Relation between genotype and phenotype with subsequent blood groups
Why AB blood group is called AB? Origination of its antigens along with role of H antigen
Antigens in blood group O and the reason why it is called blood group O?
Definition of allele, concept of dominant and recessive allele with examples and their relations with ABO blood group system