GenCircle: A Scalable Miniature Circular dsDNA Production System for Gene and Cell Therapy

Explore a groundbreaking webinar on GenCircle™, a novel miniature circular dsDNA production system for gene and cell therapy. Learn about this antibiotic resistance gene-free technology with a minimal 429bp backbone, designed to improve transfection and expression efficiency. Discover the scalable manufacturing process, optimal construct design strategies, and performance data in T cell engineering and in vivo expression. Gain insights from Dr. Fan Zhou, a senior scientist at Genscript Novel Therapeutic Materials R&D team, as he presents this innovative approach to addressing challenges in plasmid DNA production for therapeutic applications. Understand the importance of eliminating antibiotic-resistant genes in plasmid DNA for patient safety and the benefits of smaller-sized plasmid DNA in improving efficiency.

A scalable miniature circular GenCircle™ dsDNA production system for gene and cell therapy