Principles of Antibiotic Chemotherapy and Antimicrobial Stewardship

Explore the general principles of antibiotic chemotherapy in this comprehensive lecture. Gain insights into selecting appropriate antibiotics, understand important antibiotic classes and their activity spectrums, and delve into antimicrobial stewardship. Learn about the concept of the "Magic Bullet," differentiate between bacteriostatic and bactericidal antibiotics, and examine various antibiotic groups including penicillin, flucloxacillin, amoxicillin, and cephalosporins. Discover the time-dependent vs. concentration-dependent nature of antibiotics, and understand the antibiotic wheel. Investigate the risks associated with antibiotic prescriptions and the importance of antibiotic stewardship in the context of One Health. Explore strategies for improving antibiotic use, including the "Start Smart then Focus" approach, guidelines for switching medications, determining treatment duration, and implementing point-of-care tests. Enhance your knowledge of antibiotic policies, reporting practices, and communication strategies to promote responsible antibiotic use in clinical settings.

Introduction
The Magic Bullet
Choosing an antibiotic
Bacteriostatic vs bactericidal
Antibiotic Spectra
Clinical Reasoning
Antibiotic Classes
Antibiotic Groups
Penicillin
Flucloxacillin
Amoxicillin
Keflasporins
Limitations
Amino glycosides
Time dependent vs concentration dependent
Antibiotic wheel
Antimicrobial stewardship
Risks of prescribing antibiotics
Antibiotic stewardship
One Health
Reporting
Antibiotic policies
Start smart then focus
Start smart
Focus
Switch
Length of treatment
Improving antibiotic stewardship
Guidelines
Strategies
Communication
Prescriptions
Point of care tests
Survivalent system
Conclusion