Alpha-Reactivity and Condensation Reactions in Organic Chemistry - Lecture 36

Explore key concepts in organic chemistry through this 53-minute lecture from Yale University's Freshman Organic Chemistry II course. Delve into the challenges of ketone alkylation, focusing on reagent selection and controlling isomerism. Learn about β-dicarbonyl compound alkylation, aldol condensation, and the Robinson annulation reaction. Examine α-acylation of esters in the Claisen condensation and its role in fatty acid biosynthesis. Discover the complexities early carbohydrate chemists faced in determining sugar structures. The lecture covers topics such as the Soxhelet extractor, alkylation regiochemistry, conjugate addition, and carbohydrate structures, providing a comprehensive overview of α-reactivity and condensation reactions in organic chemistry.

- Chapter 1. The Soxhelet Extractor
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- Chapter 2. Alkylation Regiochemistry
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- Chapter 3. Alkylation of B-Dicarbonyl Compounds
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- Chapter 4. Aldol Condensations
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- Chapter 5. Conjugate Addition and Robinson Annulation
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- Chapter 6. Claisen Condensation and Fatty Acid Biosynthesis
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- Chapter 7. Carbohydrate Structures
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