Pediatric Grand Rounds (RECORDING) Haploidentical Stem Cell Transplantation: You�ve Always Got a Donor, Why Not Always Use It?

Stanford Center for Continuing Medical Education, Pediatric Grand Rounds (RECORDING) Haploidentical Stem Cell Transplantation: You’ve Always Got a Donor, Why Not Always Use It?, 12/15/2021 12:00:00 AM - 12/15/2022 12:00:00 AM, This presentation is a recording of a Stanford Pediatric Grand Rounds Session.  World-renowned experts will present the latest research, practice guidelines, and treatment protocols to advance best practices in the care of pediatric patients. These online recordings will provide pediatricians and family physicians with up-to-date clinical information on a wide range of clinical issues encountered in daily pediatric practice. 

Hematopoietic stem cell transplantation (HSCT) is the only curative treatment for many disorders, including malignant and non-malignant disorders. However, a fully matched related donor is available only for 25% of patients, and, despite over 31 million of volunteer donors, about 50% patients cannot find a suitable donor in a reasonable frame-time. Therefore, strategies to optimize the use of mismatched donors are urgently needed. The use of donors HLA-partially matched (haploidentical) is becoming widely used and in 2021 we can say that, thanks to new graft manipulation strategies we have a donor for everyone.