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Molecular Biology - Part 2: Transcription and Transposition

Offered By: Massachusetts Institute of Technology via edX

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Molecular Biology Courses Data Analysis Courses Gene Expression Courses Molecular Genetics Courses Experimental Design Courses CRISPR Courses

Course Description

Overview

In Part 2 of this Molecular Biology course, you’ll explore transcription of DNA to RNA, a key part of the central dogma of biology and the first step of gene expression.

Did you know that transposable elements, the genetic information that can move from location to location, make up roughly 50 % of the human genome? Did you know that scientists have linked their movement into specific genes to the causes of certain diseases? You’ll also learn how these “jumping genes” work and how scientists study them in Molecular Biology: Transcription and Transposition.

Are you ready to go beyond the “what" of scientific information presented in textbooks and explore how scientists deduce the details of these molecular models?

Take a behind-the-scenes look at modern molecular genetics, from the classic experimental events that identified the proteins and elements involved in transcription and transposition to cutting-edge assays that apply the power of genome sequencing. We've designed the problems in this course to build your experimental design and data analysis skills.

Let’s explore the limits of our current knowledge about the transcription machinery and mechanisms of transposition. If you are up for the challenge, join us in 7.28.2x Molecular Biology: Transcription and Transposition.


Syllabus

Week 1 : Machinery and Promoters of Bacterial Transcription

Week 2 : Bacterial Regulation of Bacterial Transcription

Week 3 : Machinery and Promoters of Eukaryotic Transcription

Week 4 : Regulation of Eukaryotic Transcription I

Week 5 : Regulation of Eukaryotic Transcription II

Week 6 : Transposition

Week 7 : CRISPR


Taught by

Tania A. Baker and Stephen P. Bell

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